OIL-IN-WATER EMULSION-TYPE TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING RETINOID Russian patent published in 2018 - IPC A61K9/107 A61K31/07 A61K31/40 A61K47/44 A61K47/10 A61P17/00 

Abstract RU 2655305 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to the chemical-pharmaceutical industry and is a pharmaceutical composition for treating dermatological diseases of the oil-in-water emulsion type, comprising: an oil phase containing 3"-tert-butyl-4'-(2-hydroxyethoxy)-4"-pyrrolidin-1-yl-[1,1',3',1"]-terphenyl-4-carboxylic acid, phenoxyethanol and oily auxiliary solvents; an aqueous phase comprising a surfactant from the group of sucrose esters, polyol and purified water. Said pharmaceutical composition is suitable for the treatment of acne and ichthyosis.

EFFECT: group of inventions enables to obtain physically and chemically stable pharmaceutical compositions, which demonstrate better tolerance and are easily applied to the skin of the patient, providing gradual penetration of active substances.

18 cl, 3 dwg, 16 tbl, 13 ex

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RU 2 655 305 C2

Authors

Dyupra Anes

Mallar Kler

Dates

2018-05-24Published

2013-05-30Filed