COMPOUNDS FOR IMPROVED STEM CELL DIFFERENTIATION INTO HEPATOCYTES Russian patent published in 2018 - IPC C07D401/04 A61K31/4439 C12N5/71 A61P31/20 

Abstract RU 2662954 C2

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, specifically a heterocyclic compound of general formula I or a stereoisomer thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 independently represent a hydrogen or halogen atom and R11 represents a hydrogen atom or a hydroxy group. Invention also relates to a method for differentiating stem cells into hepatocytes.

.

EFFECT: technical result: novel heterocyclic compounds are obtained for use as platforms for drug screening and for use in modeling diseases.

27 cl, 18 dwg, 1 tbl, 7 ex

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RU 2 662 954 C2

Authors

Chiao Erik

Gamilton Metyu Majkl

Kameoka Sej

Leonard Brajan

Triyatni Miriam

Dates

2018-07-31Published

2014-03-12Filed