PLANT-DERIVED REMEDY WITH SEDATIVE EFFECT Russian patent published in 2018 - IPC A61K9/20 A61K36/81 A61K36/84 A61K36/896 A61K47/38 A61P25/20 

Abstract RU 2663806 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to chemical-pharmaceutical industry and is a sedative plant-based agent based on Zelenin droplets, comprising excipients, characterized in that preliminarily dried up to residual moisture of not more than 17 % of a Zelenin droplet is used, and preparation further comprises a structure-forming complex consisting of D-mannitol, hydroxypropyl cellulose and polyvinyl alcohol, taken in equal amounts, and as tablets for the use of auxiliaries, with the following ratio of components, by weight: pre-dried to residual moisture of not more than 17 % of a drop of Zelenin 5.9–7.0; auxiliaries complex 76.0–80.0; silica colloidal dioxide 9.4–9.3; magnesium or calcium stearate 0.1–0.9; microcrystalline cellulose (MCC) – the rest up to 100 %.

EFFECT: invention allows to provide satisfactory strength, storage stability, masking of the taste of the drug.

1 cl, 4 tbl, 2 ex

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RU 2 663 806 C1

Authors

Mizina Praskovya Georgievna

Sidelnikov Nikolaj Ivanovich

Dzhavakhyan Marina Arkadevna

Gulenkov Aleksandr Sergeevich

Sajbel Olga Leonidovna

Bortnikova Valentina Vasilevna

Lupanova Irina Aleksandrovna

Trumpe Tatyana Evgenevna

Dates

2018-08-10Published

2017-11-21Filed