METHOD FOR EVALUATING THE BIOLOGICAL ACTIVITY OF A TETRADECAPEPTIDE Russian patent published in 2018 - IPC G01N33/15 

Abstract RU 2667120 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to the chemical-pharmaceutical industry, and relates to method for evaluating the biological activity of a tetradecapeptide consisting of 14 amino acid residues, of the general formula TEKKRRETVEREKE (TDP). Method for evaluating the biological activity of a TDP is that the test peptide is added to the culture of 3T3/NIH fibroblast cells in vitro followed by incubating the resulting mixture for 5 minutes and determining the degree of phosphorylation of the ERK1/2 kinase by fluorescence microscopy or by immunoblotting.

EFFECT: method for evaluating the biological activity of TDP is proposed.

1 cl, 2 dwg, 2 ex

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RU 2 667 120 C1

Authors

Chulkina Marina Mikhajlovna

Lebedeva Ekaterina Semenovna

Pichugin Aleksej Vasilevich

Kholmukhamedov Ekhson Lukmanovich

Ataullakhanov Ravshan Inoyatovich

Dudchenko Aleksandr Maksimovich

Dates

2018-09-14Published

2017-12-18Filed