FIELD: medicine.
SUBSTANCE: methods of the invention involve introduction of (R)-3-[1-(2,6-dichlor-3-fluorophenyl)ethoxy]-5-(1-piperidine-4-yl-1H-pyrazole-4-yl)pyridine-2-ylamine (Compound 1) for treating the abnormal cell expansion and inhibition of activity of kinase s-Met/HGFR in a cell.
EFFECT: application of the inventions enables to inhibit growth of tumor ensured by inhibition of genetically changed kinases of receptor of hepatocyte and anaplastic lymphoma (ALK) growth factor with compound 1.
11 cl, 5 tbl, 11 dwg, 1 ex
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Authors
Dates
2010-03-20—Published
2006-11-23—Filed