METHOD FOR USE OF N,N'-BIS(2,3-BUTADIENYL)-1,4-DIAMINOBUTANE DIHYDROCHLORIDE (MDL72.527) FOR SUPPRESSING REPLICATION OF HEPATITIS C VIRUS Russian patent published in 2018 - IPC A61K31/13 A61P1/16 A61P31/14 

Abstract RU 2667123 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and concerns a method for suppressing replication of hepatitis C virus by inhibitor of catabolism enzymes of biogenic polyamines N,N’-bis(2,3-butadienyl)-1,4-butanediamine hydrochloride (MDL72.527). Compound inhibits reproduction of hepatitis C virus in micromolar concentrations in cultures of infected cells and in culture of cells carrying a subgenomic virus replicon.

EFFECT: method provides a wider range of antiviral agents.

1 cl, 3 ex, 2 dwg

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RU 2 667 123 C1

Authors

Kochetkov Sergej Nikolaevich

Ivanov Aleksandr Vladimirovich

Smirnova Olga Aleksandrovna

Bartosh Birke

Dates

2018-09-14Published

2017-12-01Filed