FIELD: medicine.
SUBSTANCE: invention relates to medicine and concerns a method for suppressing replication of hepatitis C virus by inhibitor of catabolism enzymes of biogenic polyamines N,N’-bis(2,3-butadienyl)-1,4-butanediamine hydrochloride (MDL72.527). Compound inhibits reproduction of hepatitis C virus in micromolar concentrations in cultures of infected cells and in culture of cells carrying a subgenomic virus replicon.
EFFECT: method provides a wider range of antiviral agents.
1 cl, 3 ex, 2 dwg
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Authors
Dates
2018-09-14—Published
2017-12-01—Filed