STANDARD SAMPLE OF ANTI-A AND ANTI-B HAEMAGGLUTININ CONTENT IN PREPARATIONS OF HUMAN BLOOD Russian patent published in 2018 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, transfusiology, and can be used to determine the content of anti-A and anti-B hemagglutinins in human blood preparations in the direct hemagglutination reaction and the indirect hemagglutination reaction. For this, the kit contains five components, which are solutions of human immunoglobulins. Positive component A with a certified content of anti-A hemagglutinins in the range from 1:16 to 1:64 and a certified protein content of at least 30 mg/ml, obtained from blood plasma of donors of I(0) blood group. Positive component B with a certified content of anti-B hemagglutinins in the range from 1:16 to 1:64 and a certified protein content of at least 30 mg/ml, obtained from blood plasma of donors of the I(0) blood group. Negative component with a certified content of anti-A and anti-B hemagglutinins in an amount, corresponding to a dilution of not more than 1:2, and a certified protein content of at least 30 mg/ml, derived from blood plasma donors IV(AB) blood group. Component with an anti-A hemagglutinin content limit with a certified content of anti-A hemagglutinins in an amount, corresponding to a dilution of 1:64, and a certified protein content of at least 30 mg/ml, obtained from the blood plasma of donor of I(0) blood group. Component with an anti-B content limit of hemagglutinins with a certified content of anti-B hemagglutinins in an amount corresponding to a dilution of 1:64, and a certified protein content of at least 30 mg/ml, obtained from blood plasma of donors of I(0) blood group.

EFFECT: use of this invention makes it possible to obtain a standard sample of the anti-A and anti-B content of hemagglutinins for use in the direct haemagglutination reaction and the indirect haemagglutination reaction for assessing the quality of blood products.

1 cl, 14 ex, 5 tbl