USE OF BENZIMIDAZOLE DERIVATIVE FOR THE TREATMENT OF NOCTURNAL ACID BREAKTHROUGH Russian patent published in 2018 - IPC A61K31/4184 A61P43/00 

Abstract RU 2672248 C1

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and is intended for the prevention and treatment of nocturnal acid breakthrough (NAB). Pharmaceutical composition containing the benzimidazole derivative 4-(5,7-difluorochromane-4-yloxy)-N,N,2-trimethyl-1H-benzo[d]imidazole-6-carboxamide or its pharmaceutically acceptable salt is used. Unit dosage form containing 50 to 200 mg of 4-(5,7-difluorochromane-4-yloxy)-N,N,2-trimethyl-1H-benzo[d]imidazole-6-carboxamide or its pharmaceutically acceptable salt is also disclosed.

EFFECT: group of inventions widens the range of therapeutic agents.

11 cl, 7 tbl, 2 dwg, 2 ex

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RU 2 672 248 C1

Authors

Lee Ha Jin

Kim Bong Tae

Kim Hyun

Nam Ji Yeon

Park Jie Eun

Song Geun Seog

Ryu Shin Young

Koizumi Shinichi

Takahashi Nobuyuki

Tajimi Masaomi

Dates

2018-11-13Published

2016-06-08Filed