FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, namely to therapy and hematology, and concerns the treatment of anemia. To do this, enter the fused polypeptide containing erythropoietin (EPO) and hybrid Fc immunoglobulin. When this EPO consists of the amino acid sequence of SEQ ID NO: 1. Hybrid Fc immunoglobulin consists of the amino acid sequence of SEQ ID NO: 2. Fusion polypeptide is administered at a dose of 5 mcg/kg to 9 mcg/kg at intervals of 2 to 4 weeks.
EFFECT: introduction of such a polypeptide in a specified dose and mode of administration provides the most rapid and effective treatment of anemia in the absence of side effects.
22 cl, 4 dwg, 3 ex, 3 tbl
| Title |
Year |
Author |
Number |
| METHOD FOR INCREASING NUMBER OF LYMPHOCYTES IN TUMOURS USING HYBRID PROTEIN IL-7 |
2020 |
- Sung, Young Chul
- Woo, Jung Won
- Heo, Min Kyu
- Yang, Sang In
- Yang, Sehwan
|
RU2822396C1 |
| RECOMBINANT FUSED HUMAN PROTEIN EPO-FC WITH PROLONGED TIME OF HALF-LIFE AND INCREASED ERYTHROPOETIC ACTIVITY IN VIVO (VERSIONS), DIMERIC PROTEIN CONSTRUCTION, DIMERIC PROTEIN, PHARMACEUTICAL COMPOSITION, SEQUENCE OF NUCLEIC ACID (VERSIONS), EXPRESSION VECTOR, CELL, METHOD OF OBTAINING PROTEIN AND METHOD OF ERYTHROPOESIS STIMULATION IN MAMMAL |
2007 |
- Van Khajtao
- Du Jun
- Chzhan Zhuj
- Sjuj Tszin
- Lju Lunbin'
|
RU2433181C2 |
| PHARMACEUTICAL COMPOSITION FOR GROWTH HORMONE DEFICIENCY THERAPY COMPRISING FUSED hGH PROTEIN |
2017 |
- Kim, Tae Kyung
- Woo, Jung Won
- Lee, Joan Yoon Ji
- Ahn, Young-Joo
- Cha, Ji-Eun
- Rhim, Hyou Young
- Jang, Woo Ick
|
RU2748402C2 |
| PHARMACEUTICAL COMPOSITION COMPRISING RECOMBINANT HUMAN GROWTH HORMONE FOR TREATING GROWTH HORMONE DEFICIENCY |
2017 |
- Kim, Tae Kyung
- Ahn, Young_joo
- Woo, Jung Won
- Cha, Ji-Eun
- Lee, Joan Yoon Ji
|
RU2732113C2 |
| MODIFIED INTERLEUKIN-7 PROTEIN AND METHODS FOR USE THEREOF |
2016 |
- Yang, Se Hwan
- Choi, Donghoon
- Lim, Hye Seong
|
RU2708160C2 |
| COMBINED APPLICATION OF TRAPS OF GDF AND ERYTHROPOIETIN RECEPTOR ACTIVATORS FOR INCREASING ERYTHROCYTE CONTENT |
2010 |
- Sikhra Dzhasbir
- Pirsall Robert Skott
- Kumar Ravindra
|
RU2592670C2 |
| COMBINED ADMINISTRATION OF GDF TRAPS AND ERYTHROPOETIN RECEPTOR ACTIVATORS FOR INCREASING CONTENT OF ERYTHROCYTES |
2010 |
- Sikhra Dzhasbir
- Pirsall Robert Skott
- Kumar Ravindra
|
RU2642302C1 |
| COMBINED USE OF GDF TRAPS AND ACTIVATORS OF ERYTHROPOIETIN RECEPTORS TO INCREASE ERYTHROCYTE CONTENT |
2017 |
- Seehra, Jasbir
- Pearsall, Robert, Scott
- Kumar, Ravindra
|
RU2732229C2 |
| COMBINED USE OF GDF TRAPS AND ERYTHROPOIETIN RECEPTOR ACTIVATORS TO INCREASE ERYTHROCYTE COUNT |
2020 |
- Seehra, Jasbir
- Pearsall, Robert, Scott
- Kumar, Ravindra
|
RU2814047C2 |
| METHODS FOR TREATMENT OF DISEASE, USING BONE MORPHOGENETIC PROTEIN 6 (BMP6) INHIBITORS |
2017 |
- Cong, Feng
- Dietrich, William
- George, Nathalie
- Liu, Dong
- Schachter, Asher
- Soni, Aditi
- Zhou, Jing
|
RU2790023C2 |
