FIELD: chemistry.
SUBSTANCE: invention relates to a compound having the structure of formula (II), or a pharmaceutically acceptable salt thereof, which have the property of inhibiting histone deacetylase (HDAC) enzymes. In formula (II), RA is H or F; RC is H, Cl or F; Het is selected from oxetanyl, piperidinyl and 8-azabicyclo[3.2.1]octanyl, and if Het is piperidinyl or 8-azabicyclo[3.2.1]octanyl, then the nitrogen atom in the ring is substituted with RB; RB is CH3, CH2C(CH3)3, CH2C(OH)(CH3)2 or CH2cyclopropyl. 
(II).
EFFECT: invention also relates to particular compounds selected from said group, a pharmaceutical composition and the use of compounds for the preparation of a medicament for the treatment or prevention of a disease or condition associated with HDAC inhibition.
18 cl, 1 dwg, 4 tbl, 13 ex
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