FIELD: chemistry.
SUBSTANCE: invention relates to a method of the phosphonoacetic acid esters preparation, that can be used as starting compounds in the synthesis of phosphorus-containing biologically active substances and reagents. Proposed method of obtaining the phosphonoacetic acid trialkyl esters is the interaction of the chloroacetic acid esters with dialkyl ester of phosphorous acid under the influence of ultrasound in the presence of potassium carbonate at a molar ratio of reagents, respectively, equal to 1:1:(1–1.5).
EFFECT: proposed a new effective way to obtain valuable substances.
3 cl, 6 ex
| Title | Year | Author | Number |
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|
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| METHOD OF OBTAINING DIALKYL ESTERS OF B-TRIALKOXY-SILYL-ETHYLPHOSPHONIUM ACID | 0 |
|
SU652183A1 |
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RU2671581C1 |
| METHOD OF PRODUCING 2,2-ADAMANTYLENE SPIROOXIRANE DERIVATIVES | 2013 |
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RU2529025C1 |
| METHOD OF PREPARING CHLORACETANYLS | 0 |
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SU596162A3 |
| METHOD OF OBTAINING NITRILOTRIMETHYLPHOSPHONIC ACID | 0 |
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SU684038A1 |
| METHOD FOR PREPARING VINPOCETINE AND APOVINCAMIN | 2009 |
|
RU2497823C2 |
| PROCESS FOR PREPARING 1R, 3S-2,2-DIMETHYL-3-(2- OXOPROPYL)CYCLOPROPANEACETONITRILE | 1989 |
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RU1689376C |
