FIELD: medicine.
SUBSTANCE: group of inventions relates to the field of medicine and the chemical and pharmaceutical industry, and concerns the breast cancer treatment means. Proposed is the 3-O-sulphamoyloxy-7β-methyl-D-homo-6-oxa-8α-estra-1,3,5(10)-trien-17a-one production method, and its use as the antitumor agent in the triple negative breast cancer mono- and adjuvant therapy.
EFFECT: mammary gland ER-/PR-/HER2+ tumors growth inhibition in mice and in the triple negative breast cancer MDA-MB-231 cells growth suppression.
3 cl, 1 tbl, 2 ex
| Title |
Year |
Author |
Number |
| USE OF 3-O-SULFAMOYLOXY-7Β-METHYL-D-HOMO-6-OXAESTRA-1,3,5(10),8(9)-TETRAEN-17A-ONE FOR THE TREATMENT OF BREAST CANCER, INCLUDING A TRIPLE NEGATIVE FORM |
2018 |
- Shavva Aleksandr Grigorevich
- Morozkina Svetlana Nikolaevna
|
RU2678845C1 |
| APPLICATION OF 3-O-SULFAMATE-16,16-DIMETHYL-D-HOMOEQUILININE FOR TREATMENT OF ONCOLOGICAL DISEASES |
2018 |
- Shavva Aleksandr Grigorevich
- Morozkina Svetlana Nikolaevna
|
RU2680603C1 |
| 7β-METHYL-3,17αβ-DISULFAMOYLOXY-D-HOMO-6-OXA-ESTRA-1,3,5(10), 8,14-PENTAEN AS BREAST CANCER MCF-7 CELLS GROWTH INHIBITOR |
2016 |
- Shavva Aleksandr Grigorevich
- Morozkina Svetlana Nikolaevna
- Khotimchenko Yurij Stepanovich
|
RU2619457C1 |
| NEW METHOD FOR SYNTHESIS OF 3-O-SULPHAMATE 16,16-DIMETHYL-D-HOMOEQUILENINE |
2021 |
- Shavva Aleksandr Grigorevich
- Morozkina Svetlana Nikolaevna
|
RU2752064C1 |
| RACEMIC 2,17ALFABETA-DISULFAMOYLOXY-3-METHOXY-D-HOMO-8ALPHA-ESTRA-1,3,5 (10)-TRIENE AS MSF-7 TUMOR CELLS PROLIFERATION INHIBITOR |
2016 |
- Shavva Aleksandr Grigorevich
- Morozkina Svetlana Nikolaevna
|
RU2629186C1 |
| RACEMIC 2,17β-DISULFOMOYLOXY-3-METHOXY-8α-EXTRA-1,3,5(10)-TRIENE AS INHIBITOR OF TUMOUR CELL PROLIFERATION OF MCF-7 |
2014 |
- Morozkina Svetlana Nikolaevna
- Drozdov Andrej Sergeevich
- Kovalev Roman Aleksandrovich
- Filatov Mikhail Valentinovich
- Shavva Aleksandr Grigor'Evich
|
RU2562242C1 |
| SULFAMATE DERIVATIVES, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS |
1996 |
- Zigfrid Shvarts
- Val'Ter Ehl'Ger
- Gudrun Reddersen
- Birgitt Shnajder
- Ina Time
- Margit Rikhter
|
RU2159774C2 |
| METHOD FOR TREATMENT OF ANDROGEN RECEPTOR (AR)-POSITIVE FORMS OF BREAST CANCER USING SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARM) |
2013 |
- Dolton Dzhejms T.
- Stejner Mitchell S.
- Narayanan Ramesh
- An Suntszo
|
RU2648959C2 |
| METHOD OF TREATING ANDROGEN RECEPTOR (AR)-POSITIVE FORMS OF BREAST CANCER USING SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARM) |
2013 |
- Dalton, James, T.
- Steiner, Mitchell, S.
- Narayanan, Ramesh
- Ahn, Sunjoo
|
RU2717835C2 |
| MEDICINAL PREPARATION CONTAINING AROMATASE STEROID INHIBITOR FOR PROPHYLAXIS AND/OR TREATMENT OF MAMMARY CANCER |
1999 |
- Shmidt Al'Fred
- Viland Khajnrikh
|
RU2225206C2 |
