PHARMACEUTICAL COMBINATIONS OF CDK4/6 INHIBITOR AND B-Raf INHIBITOR Russian patent published in 2019 - IPC A61K31/4184 A61K31/136 A61K31/407 A61K31/4155 A61K31/435 A61K31/4418 A61K31/4427 A61K31/506 A61K31/519 A61P35/00 

Abstract RU 2685250 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: pharmaceutical combination comprising (a) CDK4/6 inhibitor, (b) a B-Raf inhibitor, and optionally (c) a MEK 1/2 inhibitor; combined preparations and pharmaceutical compositions thereof; use of such a combination in the treatment of proliferative diseases; methods of treating subjects suffering from proliferative diseases comprising administering a therapeutically effective amount of such combination.

EFFECT: treatment of proliferative diseases.

10 cl, 4 ex, 1 dwg

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RU 2 685 250 C2

Authors

Kaponigro Dzhordano

Styuart Darrin

Kim Sunkiu

Loo Elis

Delech Skott

Dates

2019-04-17Published

2013-07-25Filed