FIELD: medicine; pharmaceuticals.
SUBSTANCE: pharmaceutical combination comprising (a) CDK4/6 inhibitor, (b) a B-Raf inhibitor, and optionally (c) a MEK 1/2 inhibitor; combined preparations and pharmaceutical compositions thereof; use of such a combination in the treatment of proliferative diseases; methods of treating subjects suffering from proliferative diseases comprising administering a therapeutically effective amount of such combination.
EFFECT: treatment of proliferative diseases.
10 cl, 4 ex, 1 dwg
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Authors
Dates
2019-04-17—Published
2013-07-25—Filed