FIELD: biotechnology.
SUBSTANCE: invention relates to a method for producing a mutant strain of Mycoplasma hyopneumoniae, to carrier vectors used in said method, strains produced by said method, a vaccine, a kit for vaccination, use thereof for treating enzootic pneumonia and other diseases of pigs. Method for producing a mutant strain of Mycoplasma hyopneumoniae comprises a step of transforming M. hyopneumoniae strain by using a carrier vector comprising at least one exogenous DNA sequence, which is a sequence under control of the Mhyo promoter region DNA sequence containing 50 to 300 base pairs located on 5'-end of the Mhyo protein gene selected from the group formed by the P36, P46, P65, P76, P97, P102, P146 and P216 proteins.
EFFECT: proposed inventions can be used in biotechnology, veterinary science.
34 cl, 14 dwg, 2 tbl, 8 ex
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| COMPOSITION FOR PREVENTING AND CURING MYCOPLASMA SPP INFECTION | 2013 |
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| POLYVALENT RECOMBINANT SWINE POX VIRUS | 2017 |
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| CONJUGATES OF GHRELIN CARRIER | 2003 |
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| RECOMBINANT MICROORGANISM WITH INCREASED ABILITY TO PRODUCE PUTRESCINE, AND METHOD OF PRODUCING PUTRESCINE USING SAID MICROORGANISM | 2013 |
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| METHOD OF OBTAINING A RECOMBINANT VACCINE FOR PREVENTION OF HUMANPAPILLOMA VIRUS INFECTION, RECOMBINANT VACCINE | 2018 |
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RU2681174C1 |
