FIELD: biotechnology.
SUBSTANCE: inventions relate to the field of biotechnology and relate to a vaccine composition, an immunization method using said composition and a kit for carrying out such a method. Present vaccine composition contains an effective amount of an ORF2 polypeptide of a highly virulent divergent strain of porcine circovirus type 2b (PCV2b) encoded by a genomic sequence that has at least 95 % sequence identity with SEQ ID NO: 66, wherein the encoded ORF2 polypeptide comprises leucine (L) at position 89, threonine (T) at position 90, and asparagine (N) at position 134 in accordance with the numeration of SEQ ID NO: 1; and an oil-in-water emulsion adjuvant.
EFFECT: inventions can be used to provide protection of pigs against swine circovirus type 2 (PCV2), including protection against PCV2b.
17 cl, 7 dwg, 23 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHODS AND COMPOSITIONS FOR IMMUNISATION OF PIGS AGAINST PORCINE CIRCOVIRUS | 2008 |
|
RU2493254C9 |
| MYCOPLASMA HYOPNEUMONIAE VACCINE | 2013 |
|
RU2644254C2 |
| COMBINATION VACCINE PCV/MYCOPLASMA HYOPNEUMONIAE/PRRS (PCV/MYCOPLASMA HYOPNEUMONIAE/PRRS COMBINATION VACCINE) | 2013 |
|
RU2644256C2 |
| COMBINED VACCINE PCV/MYCOPLASMA HYOPNEUMONIAE | 2013 |
|
RU2615443C2 |
| RECOMBINANT VIRUS-LIKE CIRCOVIRUS CAPSID PARTICLE (VLP): COMPOSITIONS, METHODS AND USES | 2020 |
|
RU2817679C2 |
| POLYVALENT RECOMBINANT SWINE POX VIRUS | 2017 |
|
RU2766008C2 |
| FUSED POLYPEPTIDES AND VACCINES | 2014 |
|
RU2699006C2 |
| PCV2 IMMUNOGENIC COMPOSITIONS AND METHODS OF SUCH COMPOSITIONS PRODUCTION | 2005 |
|
RU2620968C9 |
| IMMUNOGENIC COMPOSITIONS PCV2 AND METHODS FOR PRODUCING SUCH COMPOSITIONS | 2005 |
|
RU2435854C2 |
| RECOMBINANT EXPRESSION OF PROTEIN ORF2 PCV2b IN INSECT CELLS | 2018 |
|
RU2779423C2 |
