ANTIBODIES TO COMPLEMENT COMPONENT C5 Russian patent published in 2019 - IPC C07K16/18 A61K39/395 

Abstract RU 2693430 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology and represents a C5 antibody or a fragment thereof, wherein the antibody or fragment thereof specifically binds to C5 and inhibits complement-dependent haemolysis, but does not block the formation of C5a, wherein the antibody comprises a first amino acid sequence and a second amino acid sequence. Invention also relates to a method of treating or reducing cases of eye disease associated with complement activation. Method involves administering an effective amount of the antibody to a patient and thereby treating or reducing the incidence of the disease.

EFFECT: higher efficiency of treatment.

17 cl, 14 dwg, 5 tbl, 14 ex

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RU 2 693 430 C2

Authors

Batsiu Piter S.

Lyan Yanbin

Gu Dzhejson

Bernett Metyu

Muchkhal Umesh

Deszharlajs Dzhon

Dates

2019-07-02Published

2015-02-19Filed