FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and represents a C5 antibody or a fragment thereof, wherein the antibody or fragment thereof specifically binds to C5 and inhibits complement-dependent haemolysis, but does not block the formation of C5a, wherein the antibody comprises a first amino acid sequence and a second amino acid sequence. Invention also relates to a method of treating or reducing cases of eye disease associated with complement activation. Method involves administering an effective amount of the antibody to a patient and thereby treating or reducing the incidence of the disease.
EFFECT: higher efficiency of treatment.
17 cl, 14 dwg, 5 tbl, 14 ex
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Authors
Dates
2019-07-02—Published
2015-02-19—Filed