HUMANIZED ANTIBODY TO CONFORMATIONAL C3 EPITOPE CONSTITUENT OF HUMAN COMPLEMENT, DNA SEQUENCE (VERSIONS), EXPRESSION VECTOR CONTAINING DNA SEQUENCE (VERSIONS), AND OVARIAN CELLS' STRAIN OF CHINESE HAMSTER CHO-HUMC34-PRODUCER OF THIS HUMANIZED ANTIBODY Russian patent published in 2017 - IPC C07K16/18 C12N15/00 C12N15/10 C12N15/74 C12N15/84 A61K39/395 

Abstract RU 2630647 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a humanized antibody, which binds to the C3 epitope of the human complement component. DNA encoding the mentioned antibody, an expression vector, for expressing the mentioned antibody, and also a ovarian cells' strain of chinese hamster which produces the mentioned antibody are also disclosed.

EFFECT: invention has the ability to bind specifically to the C3 epitope of the human complement component, which allows the effective treatment of diseases associated with the C3 component of the human complement.

12 cl, 6 dwg, 3 ex

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RU 2 630 647 C1

Authors

Kartuzova Valeriya Evgenevna

Trofimov Aleksandr Viktorovich

Ishchenko Aleksandr Mitrofanovich

Rodin Sergej Vladimirovich

Zhakhov Aleksandr Vladimirovich

Simbirtsev Andrej Semenovich

Klimov Nikolaj Anatolevich

Petrov Aleksandr Vladimirovich

Karasev Maksim Mikhajlovich

Dates

2017-09-11Published

2016-05-27Filed