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2 696 869

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IPC

A61K31/4188(2006-01-01)

A61K9/20(2006-01-01)

A61P7/02(2006-01-01)

(21) (22)

Application

2019106346, 2019-03-05

(24)

Start date

2019-03-05

(22)

Actual filing date

2019-03-05

(45)

Published

2019-08-07

(72)

Inventor

Stepanova Eleonora FedorovnaRemezova Irina PetrovnaSpasov Aleksandr AlekseevichKucheryavenko Aida FatikhovnaSmirnova Lyudmila AndreevnaGajdukova Kseniya AndreevnaSirotenko Viktor SergeevichPetrov Vladimir IvanovichMorozov Andrej VladimirovichShevchenko Aleksandr Mikhajlovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

PHARMACEUTICAL COMPOSITION OF ANTITHROMBOTIC ACTION IN SOLID DOSAGE FORM IN THE FORM OF TABLETS Russian patent published in 2019 - IPC A61K31/4188 A61K9/20 A61P7/02

Abstract RU 2696869 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to chemical-pharmaceutical industry, medicine, pharmacology and represents a solid dosage form presented in the form of tablets, antithrombotic action, characterized by that the active ingredient contains 9-(3,4-dihydroxy)phenacyl-2,3-dihydroimidazo[1,2-a]benzimidazole hydrobromide substance in following ratio of components, wt. %: 9-(3,4-dihydroxy)phenacyl-2,3-dihydroimidazo[1,2-a]benzimidazole hydrobromide – 72.17; lactose monohydrate – 8.02; calcium phosphate disubstituted – 13.37; corn starch – 4.54; plasdone K 29/32 with 10 % water – 1.50; calcium stearate – 0.40; and provides a combined mechanism of pharmacological action by blocking P₂Y₁₂ receptor and thromboxane synthesis inhibition.

EFFECT: invention provides extending the range of antithrombotics.

1 cl, 2 dwg, 7 tbl

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RU 2 696 869 C1

Authors

Stepanova Eleonora Fedorovna

Remezova Irina Petrovna

Spasov Aleksandr Alekseevich

Kucheryavenko Aida Fatikhovna

Smirnova Lyudmila Andreevna

Gajdukova Kseniya Andreevna

Sirotenko Viktor Sergeevich

Petrov Vladimir Ivanovich

Morozov Andrej Vladimirovich

Shevchenko Aleksandr Mikhajlovich

Dates

2019-08-07—Published

2019-03-05—Filed