VARIANT AAV, COMPOSITIONS AND METHODS, IN WHICH IT IS USED, AS WELL AS METHODS OF ITS APPLICATION FOR TRANSFER OF GENES INTO CELLS, ORGANS AND TISSUES Russian patent published in 2019 - IPC C07K14/15 C07K14/745 C12N7/04 C12N15/861 A61K38/36 A61K48/00 A61P7/04

Abstract RU 2697444 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to vectors based on the serotype AAV-Rh74 adenoassociated virus (AAV) containing a polynucleotide sequence coding human factor IX and can be used in medicine.

EFFECT: obtained particles are used in a pharmaceutical composition for effective treatment of hemophilia B.

21 cl, 7 dwg, 4 tbl, 9 ex

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RU 2 697 444 C2

Authors

Khaj Ketrin A.

Yazisioglu Mustafa N.

Angela Khaver

Dates

2019-08-14—Published

2014-07-22—Filed