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2 708 690

(13)

(51)

IPC

C07D495/04(2006-01-01)

A61K31/38(2006-01-01)

A61P11/00(2006-01-01)

(21) (22)

Application

2016107721, 2014-08-05

(24)

Start date

2014-08-05

(22)

Actual filing date

2014-08-05

(45)

Published

2019-12-11

(72)

Inventor

Van Der Plas Stiven EmielMartina Sebasten Loran KsaveDropsit-Montover Sebasten Zhan-Zhak SedrikEndryus Martin Dzhejms InglisKelgtermans Khans

(73)

Holder

Galapagos Nv

DERIVATIVES OF THIENO[2,3-C]PYRANS AS CFTR MODULATORS Russian patent published in 2019 - IPC C07D495/04 A61K31/38 A61P11/00

Abstract RU 2708690 C2

FIELD: chemistry.

SUBSTANCE: invention refers to compounds specified in: N-(3-carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-5-carboxamide and 2- (2-hydroxybenzamido)-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide.

EFFECT: treating cystic fibrosis or chronic obstructive pulmonary disease (COPD).

5 cl, 21 dwg

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RU 2 708 690 C2

Authors

Van Der Plas Stiven Emiel

Martina Sebasten Loran Ksave

Dropsit-Montover Sebasten Zhan-Zhak Sedrik

Endryus Martin Dzhejms Inglis

Kelgtermans Khans

Dates

2019-12-11—Published

2014-08-05—Filed