FIELD: biotechnology.
SUBSTANCE: invention refers to biotechnology and medicine, namely to producing an angioprotective and nootropic agent in the form of a solid dosage form for oral administration. Method involves separate granulation of 150–600 mg of troxerutin and 5–10 mg of vinpocetine by mixing each of them with a filler selected from polyethylene glycol-6000, sorbitol or mixtures thereof, until homogeneous, mixing with 1–5 % binder solution, selected from sodium salt of carboxymethyl starch, polyethylene oxide, followed by drying in a fluidised bed at temperature of 100 °C, after which the obtained granules are powdered with at least one antifriction agent, such as aerosil, tween-80, magnesium stearate, and pressed to obtain a solid dosage form.
EFFECT: invention widens the range of equipment.
3 cl, 2 tbl, 4 ex
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