HETEROCYCLIC COMPOUNDS AND USE THEREOF FOR PREVENTING OR TREATING BACTERIAL INFECTIONS Russian patent published in 2020 - IPC C07D471/18 C07D513/18 A61K31/439 A61P31/04 

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula (A2)

(A2),

in which • X, identical or different, independently represent O or S; • R¹ is a hydrogen atom; • R², identical or different, independently represent -(CH₂)_qOQ⁵, -(C(O))_w(CH₂)_v-C(O)OQ⁵, -(C(O))_w(CH₂)_v-C(O)NQ⁵Q⁶, (CH₂)_q-NHC(O)OQ⁵, -(CH₂)_qNQ⁵Q⁶, -(CH₂)_q-NH-C(NHQ³)=NQ⁴; or R², identical or different, independently unsubstituted or substituted with one or more T², independently represent -(C(O))_w-C₁-C₃-alkyl, -(C(O))_w-(CH₂)_p- (4-, 5- or 6-membered aromatic, saturated, completely or partially unsaturated heterocycle); • R³ is SO₃H; • Q³ and Q⁴, identical or different, independently represent a hydrogen atom or C₁-C₃-alkyl; • Q⁵ and Q⁶, identical or different, independently represent a hydrogen atom; or C₁-C₄-alkyl; • T², identical or different, independently represent OH, NH₂ or CONH₂; • p, identical or different, are independently equal to 0, 1, 2 or 3; • q, identical or different, are independently equal to 2 or 3; • v, identical or different, are independently equal to 1, 2 or 3; • w is equal to 0; and pharmaceutically acceptable salts thereof, as antibacterial agents.

EFFECT: preventing or treating bacterial infections.

16 cl, 4 tbl, 7 ex