THREE-DIMENSIONAL MODELING METHOD FOR 3D PRINTING WHEN PLANNING PANCREATIC RESECTION IN PATIENTS WITH TUMOR INVOLVEMENT Russian patent published in 2020 - IPC G16H50/00 A61B34/10 B33Y50/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, radiation diagnostics and can be used for 3D modeling for 3D printing when planning resections of pancreas in patients with tumor involvement. It is followed by CT with intravenous bolus contrast enhancement of hepatopancreatibiliary zone by low-dose protocol to obtain phases of maximum density gradient in arteries and veins of portal system. Obtained CT images are loaded into Myrian program and anatomical segmentation of image is performed. In the first phase of contrast amplification, the arterial bed is separated, in the second phase – the portal system. 3D area of interest is created and an automatic "hepatic artery" protocol is used to isolate the arteries of the celiac-mesenterial system, as well as an automatic protocol for the portal vein "portal vein, solid filter" separation. Pancreas is separated into a phase of maximum gradient with surrounding healthy tissues. Further, the tumor is recovered using the three-dimensional interpolation method with delineation of the formation at several levels depending on the size and shape. Obtained areas of interest: arteries, veins, and tumor are displayed on one screen of three-dimensional rendering called "surface area of interest" by transportation of missing object from other phase of contrast amplification. Obtained virtual model is evaluated for presence of errors in the image by comparison with axial CT sections. Further, the obtained three-dimensional model is stored in segmentation format and loaded into the Materialize program to create a three-dimensional printing file STL-file. Obtained file is loaded into 3D print program FlashPrint and sent to 3D printer FlashForge Dreamer. On the obtained three-dimensional model, supporting structures which were created automatically in FlashPrint are deleted.

EFFECT: method provides planning of pancreatic resections in patients with tumor involvement by printing a three-dimensional model of the region of interest.

1 cl, 11 dwg, 1 ex