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2 727 508

(13)

(51)

IPC

C07C69/157(2006-01-01)

C07C211/63(2006-01-01)

C07C211/62(2006-01-01)

A61K31/616(2006-01-01)

A61P7/02(2006-01-01)

(21) (22)

Application

2019104509, 2019-02-18

(24)

Start date

2019-02-18

(22)

Actual filing date

2019-02-18

(45)

Published

2020-07-22

(72)

Inventor

Urakov Aleksandr LivievichSamorodov Aleksandr VladimirovichBashirova Linara IrekovnaUrakova Natalya AleksandrovnaPurygin Petr PetrovichErmokhin Vladimir AnatolevichBondareva Nataliya Aleksandrovna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Natsionalnyj Issledovatelskij Universitet Imeni Akademika S.P. Koroleva"

AGENT EXHIBITING ANTIAGGREGATORY ACTIVITY Russian patent published in 2020 - IPC C07C69/157 C07C211/63 C07C211/62 A61K31/616 A61P7/02

Abstract RU 2727508 C1

FIELD: chemistry; medicine.

SUBSTANCE: invention refers to chemistry and medicine, namely to pharmaceutical chemistry and pharmacology. Summary: application of L-proline (L-proline acetylsalicylate) or L-tyrosine (L-tyrosine acetylsalicylate) of general formula presented below, as an agent exhibiting antiaggregatory activity. Compounds of the invention exhibit antiaggregatory activity superior to acetylsalicylic acid (see Table 1).

EFFECT: invention can be used for creating new drug preparations for preventing thrombosis and thromboembolic complications.

1 cl, 3 ex, 1 tbl

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RU 2 727 508 C1

Authors

Urakov Aleksandr Livievich

Samorodov Aleksandr Vladimirovich

Bashirova Linara Irekovna

Urakova Natalya Aleksandrovna

Purygin Petr Petrovich

Ermokhin Vladimir Anatolevich

Bondareva Nataliya Aleksandrovna

Dates

2020-07-22—Published

2019-02-18—Filed