FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to topical agents for treating infectious vaginitis. Presented is a topical agent for treating infectious vaginitis containing 0.1 % by weight of a biocidal peptide of formula H2N-(CH2)10-CO-Ile-Leu-Pro-D-Phe-Lys-D-Phe-Pro-D-Phe-D-Phe-Pro-D-Phe-Arg-Arg-NH2 and 1.5 wt. % hydroxyethyl cellulose in 0.15 M lactate buffer solution.
EFFECT: invention enables to obtain an agent with a homogeneous and plastic gel base, an active raw substance output of not less than 75 %, maintaining pH 3_5–4_5.
1 cl, 6 tbl, 3 ex
Title | Year | Author | Number |
---|---|---|---|
AGENT POSSESSING BIOCIDAL ACTION | 2017 |
|
RU2673807C2 |
BIOCIDAL PEPTIDE AND THE PREPARATION ON ITS BASIS | 2017 |
|
RU2678985C2 |
PHARMACEUTICAL COMPOSITION | 2012 |
|
RU2605288C2 |
COMPOSITION AND METHOD FOR TREATING VAGINITIS | 1991 |
|
RU2032402C1 |
MEDICINE FOR BACTERIAL VAGINOSIS (VARIANTS) | 2007 |
|
RU2325148C1 |
VAGINAL CONTRACEPTIVE | 2000 |
|
RU2173142C1 |
COMPOSITIONS AND METHODS FOR PREVENTING RADIATION DAMAGE AND STIMULATING TISSUE REGENERATION | 2018 |
|
RU2772456C2 |
BACTERICIDAL PHARMACEUTICAL COMPOSITION FOR TOPICAL APPLICATION IN THE FORM OF AN ENDOLYSIN-CONTAINING BACTERICIDAL GEL | 2021 |
|
RU2781050C1 |
COMPOSITIONS AND METHODS FOR ENTRAPPING AND INACTIVATION OF PATHOGENIC MICROORGANISMS AND SPERMATOZOIDS | 2001 |
|
RU2274442C2 |
COMPOSITION AND METHOD TO CONTROL AND MAINTAIN BACTERIAL MICROFLORA AND ACIDITY OF VAGINA | 2006 |
|
RU2409368C2 |
Authors
Dates
2020-08-14—Published
2019-10-08—Filed