STABLE AQUEOUS PHARMACEUTICAL COMPOSITION FOR INHALATIONS CONTAINING A HEXAPEPTIDE Russian patent published in 2020 - IPC A61K9/72 A61K38/08 A61P11/00 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to pulmonology and infectious diseases, and is intended for treating pulmonary disease in a subject. For the treatment of pulmonary disease in a subject, a stable pharmaceutical aqueous composition for inhalations containing 0.1 mg/ml to 100 mg/ml of a hexapeptide of formula H-Tyr-D-Ala-Gly-Phe-Leu-Arg-OH (I) or a pharmaceutically acceptable salt thereof is used. Composition has pH from 3.0 to 8.5. Method of treating pulmonary disease in a subject in need thereof involves administering to said subject a therapeutically effective amount of said stable pharmaceutical aqueous composition for inhalations.

EFFECT: use of the group of inventions provides targeted delivery of the active substance into the lungs and multiple increases therapeutic levels of the hexapeptide (I) in the lungs compared to those achieved by injecting the hexapeptide in the same dose.

7 cl, 8 tbl, 10 ex, 2 dwg