FIELD: immunology.
SUBSTANCE: disclosed is an antibody specifically binding to PD-1 and characterized by CDR amino acid sequences. Also disclosed are: a DNA molecule, a bispecific molecule, a pharmaceutical composition and use of a preparation containing an antibody, bispecific molecule and pharmaceutical composition as a drug for treating PD-1-mediated disease or condition.
EFFECT: present group of inventions can find further application in therapy of various diseases, including cancer and infectious diseases.
16 cl, 14 dwg, 5 tbl, 7 ex
Title | Year | Author | Number |
---|---|---|---|
ANTIBODIES AGAINST LIGAND-1 PROGRAMMED DEATH (PD-L1) AND APPLICATION THEREOF | 2017 |
|
RU2721582C1 |
ANTI-PD-L1 ANTIBODY AND ITS USE | 2020 |
|
RU2783685C2 |
NEW ANTIBODY COMPOSITIONS FOR CANCER IMMUNOTHERAPY | 2019 |
|
RU2804490C2 |
PHARMACEUTICAL COMPOSITION OF THE FUSION PROTEIN OF THE TRANSFORMING GROWTH FACTOR BETA RECEPTOR AND ITS APPLICATION | 2019 |
|
RU2791683C2 |
ANTIBODY TO PD-1, ITS ANTIGEN-BINDING FRAGMENT AND ITS PHARMACEUTICAL USE | 2020 |
|
RU2807484C2 |
ANTIBODIES AGAINST PD-L1 AND THEIR OPTIONS | 2017 |
|
RU2770590C2 |
ANTIBODY TO PD-L1, ITS ANTIGEN-BINDING FRAGMENT, AND THEIR PHARMACEUTICAL USE | 2019 |
|
RU2778085C2 |
PROGRAMMED CELL DEATH (PD-1) PROTEIN-1 ANTIBODIES AND USE THEREOF | 2017 |
|
RU2725950C1 |
NOVEL PROTEIN COMPOSITIONS OBTAINED BY RATIONAL DESIGN | 2019 |
|
RU2816719C2 |
ANTIBODY AGAINST CLAUDIN 18A2 AND ITS USE | 2020 |
|
RU2811431C2 |
Authors
Dates
2020-12-28—Published
2017-07-06—Filed