ANTIBODIES AGAINST PD-L1 AND THEIR OPTIONS Russian patent published in 2022 - IPC C07K16/28 A61K39/395 G01N33/577 A61P35/00 

Abstract RU 2770590 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to an antibody against programmed cell death ligand-1 (hereinafter – PD-L1) that specifically binds PD-L1, as well as to an immunoconjugate and a composition containing it. A method for producing the above-mentioned antibody is also disclosed. The invention also relates to an isolated nucleic acid molecule encoding the antibody against PD-L1, as well as to a vector and a cell containing the above-mentioned molecule.

EFFECT: invention is effective for the detection of PD-L1 protein in a patient’s sample, as well as for the treatment of cancer in a subject.

36 cl, 22 dwg, 12 tbl, 18 ex

Similar patents RU2770590C2

Title Year Author Number
ANTI-TIGIT ANTIBODIES AND METHODS OF USING 2016
  • Grogan, Jane, L.
  • Johnston, Robert, J.
  • Wu, Yan
  • Liang, Wei-Ching
  • Lupardus, Patrick
  • Yadav, Mahesh
  • Seshasayee, Dhaya
  • Hazen, Meredith
RU2732591C2
COMBINATION THERAPY OF ANTIBODY TO PROGASTRIN AND IMMUNOTHERAPY FOR CANCER TREATMENT 2018
  • Prier, Aleksandr
RU2784604C2
ANTIBODIES TO ICOS 2016
  • Sazinsky, Stephen
  • Michaelson, Jennifer S.
  • Sathyanarayanan, Sriram
  • Elpek, Kutlu Goksu
RU2742241C2
ANTIBODIES AGAINST LIGAND-1 PROGRAMMED DEATH (PD-L1) AND APPLICATION THEREOF 2017
  • Pak, Che Yn
  • Tsoj, Su A
  • Li, Chisu
  • Li, Khen Mi
  • Li, Si Khen
  • Pek, Ki Son
  • Kim, En Chul
  • Pak, Bum-Chan
  • Lim, Chon Chkhe
  • Cho, Yun-Giu
  • Pak, Yun U
RU2721582C1
BISPECIFIC ANTIGEN-BINDING MOLECULES CONTAINING ANTI-FAP CLONE 212 2019
  • Bruenker Peter
  • Duerr Harald
  • Klein Christian
  • Umana Pablo
  • Bujotzek Alexander
  • Zielonka Joerg
  • Trumpfheller Christine
  • Rapp Moritz
  • Le Clech Marine
RU2799429C2
COMBINATION OF PD-1 ANTAGONIST AND ERIBULIN FOR TREATING CANCER 2016
  • Matsui, Junji
  • Aktan, Gursel
  • Karantza, Vassiliki
  • Yuan, Ruirong
  • Funahashi, Yasuhiro
  • Berrak, Erhan
RU2737216C2
ANTI-PD-1 ANTIBODIES 2017
  • Jiang, Weidong
  • Lin, Pei-Hua
  • Tseng, Chi-Ling
RU2752832C2
BISPECIFIC ANTIBODIES TO CCL2 2020
  • Feng Shu
  • Fischer Jens
  • Gan Siok Wan
  • Georges Guy
  • Gertz Michael
  • Ho Wei Shiong Adrian
  • Jochner Anton
  • Jordan Gregor
  • Kettenberger Hubert
  • Lam Runyi Adeline
  • Majety Meher
  • Moelleken Joerg
  • Runza Valeria
  • Schaefer Martin
  • Schlothauer Tilman
  • Tiefenthaler Georg
  • Viert Maria
RU2819613C1
ANTIBODIES TO DOGS' PD-1 2014
  • Morsi Mokhamad
  • Chzhan Yuanchzhen
  • Bartels-Morozov Deniz
  • Erskin Dzhejson
  • Tarpi Ian
RU2732604C2
PD-L1 ANTIBODIES BINDING DOG PD-L1 2015
  • Morsey, Mohamad
  • Zhang, Yuanzheng
  • Bartels Morozov, Denise
  • Erskine, Jason
  • Tarpey, Ian
RU2722562C2

RU 2 770 590 C2

Authors

Jiang, Weidong

Lin, Pei-Hua

Tseng, Chi-Ling

Dates

2022-04-18Published

2017-10-14Filed