AFUCOSYLATED FIBROBLAST GROWTH FACTOR FGFR2IIIB RECEPTOR Russian patent published in 2021 - IPC C07K16/28 A61K39/00 

Abstract RU 2740714 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to a method of treating cancer, wherein cancer involves a solid tumor that overexpresses FGFR2IIIb. Also disclosed are use of afucosylated antibody which binds to FGFR2IIIb for treating cancer in an individual, where cancer is a solid tumor, which overexpresses FGFR2IIIb, a kit for treating cancer in an individual, wherein the cancer is a solid tumor that overexpresses FGFR2IIIb.

EFFECT: invention provides effective treatment of cancer associated with overexpression of FGFR2IIIb.

69 cl, 6 ex, 4 tbl, 11 dwg

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RU 2 740 714 C2

Authors

Harding, Thomas

Pierce, Kristen

Patil, Namrata

Brennan, Thomas

Hambleton, Julie

Dates

2021-01-20Published

2014-07-31Filed