METHODS AND COMPOSITIONS FOR TREATMENT OF AMYLOIDOSES Russian patent published in 2021 - IPC A61K39/395 C07K16/18 A61K49/16 A61P43/00 

Abstract RU 2746812 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to methods of treating diseases accompanied by the deposition of amyloid, in particular primary amyloidosis, to a method for detecting the presence of amyloid deposits of primary amyloidosis, to a method of reducing the amount of deposits of fibrillar aggregates formed by light chains of the kappa and / or lambda type in a patient with a diagnosis of primary amyloidosis; and a method for treating amyloid light-chain amyloidosis (ALA) with heart disease in a patient where ALA does not achieve hematologic remission by the use of a chimeric (mouse and human) antibody to amyloid fibrils.

EFFECT: invention provides an effective treatment of diseases associated with amyloid deposition, in particular primary amyloidosis.

30 cl, 14 dwg, 13 tbl, 10 ex

Similar patents RU2746812C1

Title Year Author Number
CHIMERIC ANTIBODIES FOR TREATMENT OF DISEASES CHARACTERIZED BY AMYLOIDE DEPOSITION 2018
  • Dzhons Tarran
  • Levi Elison
  • O'Brajen Shevon
RU2746325C1
PREVENTION AND TREATMENT OF CEREBRAL AMYLOID ANGIOPATHY 2008
  • Shreter Salli
  • Gejms Kejt Dora
RU2523894C2
HUMANISED ANTIBODY 2008
  • Marija Pil'Gren
  • Andrea Pfajfer
  • Andreas Mus
  • Rajan Uotts
RU2538709C2
APPLICATION OF ANTIBODY AGAINST AMYLOID-BETA IN CASE OF EYE DISEASES 2008
  • Marija Pil'Gren
  • Andrea Pfajfer
  • Andreas Mus
  • Rajan Uotts
RU2571859C2
HUMANISED ANTIBODY TO BETA AMYLOID 2007
  • Pfajfer Andrea
  • Pil'Gren Marija
  • Mus Andreas
  • Uotts Rajan
RU2498999C2
HUMANISED ANTIBODIES TO AMYLOID BETA 2008
  • Andrea Pfajfer
  • Marija Pil'Gren
  • Andreas Mus
  • Rajan Uotts
RU2567151C2
HUMANIZED ANTIBODY TO BETA AMYLOID 2013
  • Pfajfer Andrea
  • Pilgren Mariya
  • Mus Andreas
  • Uotts Rajan
RU2668161C2
USING ANTI-AMYLOID BETA ANTIBODY IN OPHTHALMIC DISEASES 2008
  • Marija Pil'Gren
  • Andrea Pfajfer
  • Andreas Mus
  • Rajan Uotts
RU2542967C2
ANTI-C5 ANTIBODIES AND THEIR USE 2018
  • Song, Wenchao
  • Sato, Sayaka
  • Miwa, Takashi
  • Guillipalli, Damodar
RU2774716C2
HUMANIZED MONOCLONAL ANTIBODY AGAINST Aβ AND ITS USE 2020
  • Feng, Xiao
  • Liang, Yangqiu
  • Jin, Lei
  • Sun, Dawei
  • Wang, Tao
  • Xiao, Liang
  • Liu, Shuang
  • Chen, Yuheng
  • Li, Zhengyi
RU2783528C1

RU 2 746 812 C1

Authors

Lentzsch Suzanne

Dates

2021-04-21Published

2018-07-24Filed