FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to recombinant follicle-stimulating hormone (FSH), and can be used in veterinary medicine to synchronize estrus and superovulation in an animal. Two fusion proteins of FSH pFSHbeta have been proposed: pFSHalpha-L-Fc)2 and (pFSHalpha: pFSHbeta-L-Fc)2 presented in the form of divalent homodimers.
EFFECT: invention provides the production of recombinant FSH with a longer half-life compared to the half-life of natural porcine FSH.
8 cl, 3 dwg, 6 tbl, 9 ex
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