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(11)

2 747 644

(13)

(51)

IPC

C07D401/14(2006-01-01)

C07D403/14(2006-01-01)

A61K31/5513(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2018113716, 2016-09-22

(24)

Start date

2016-09-22

(22)

Actual filing date

2016-09-22

(45)

Published

2021-05-11

(72)

Inventor

Angibaud, Patrick, ReneBroggini, Diego, Fernando, DomenicoCuyckens, Filip, Albert, CHostyn, Steven, AnnaJones, Russell, MarkQuerolle, Olivier, Alexis, GeorgesVermeulen, Wim

(73)

Holder

Janssen Pharmaceutica Nv

BIGETEROARYL-SUBSTITUTED 1,4-BENZODIAZEPINES AND WAYS OF THEIR USE FOR CANCER TREATMENT Russian patent published in 2021 - IPC C07D401/14 C07D403/14 A61K31/5513 A61P35/00

Abstract RU 2747644 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to new compounds of Formula (I), to pharmaceutical compositions containing the specified compounds, and to the use of the compounds in the treatment of diseases mediated by FGFR activity, such as cancer.

EFFECT: invention can be used in the treatment of diseases mediated by FGFR activity, such as cancer.

20 cl, 3 tbl, 4 ex

(I)

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RU 2 747 644 C2

Authors

Angibaud, Patrick, Rene

Broggini, Diego, Fernando, Domenico

Cuyckens, Filip, Albert, C

Hostyn, Steven, Anna

Jones, Russell, Mark

Querolle, Olivier, Alexis, Georges

Vermeulen, Wim

Dates

2021-05-11—Published

2016-09-22—Filed