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(19)

(11)

2 748 549

(13)

(51)

IPC

A61K31/47(2006-01-01)

A61K9/20(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2018140055, 2017-04-17

(24)

Start date

2017-04-17

(22)

Actual filing date

2017-04-17

(45)

Published

2021-05-26

(72)

Inventor

Aftab, Dana, T.Schwab, GiselaHessel, ColinScheffold, ChristianLacy, StevenMiles, DaleArroyo, AlanDean, Mark

(73)

Holder

Exelixis, Inc.

METHOD OF RENAL CELL CARCINOMA TREATMENT USING N-(4-(6,7-DIMETHOXYQUINOLINE-4-ILOXY)PHENYL)-N' - (4-FLUOROPHENYL)CYCLOPROPANE-1,1-DICARBOXAMIDE, (2S) - HYDROXYBUTANEDIOATE Russian patent published in 2021 - IPC A61K31/47 A61K9/20 A61P35/00

Abstract RU 2748549 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to the use of cabozantinib or a pharmaceutically acceptable salt thereof for treatment of advanced renal cell carcinoma with metastases to bone or internal organs in a human patient who has previously received anti-angiogenic therapy.

EFFECT: effective agent in renal cell carcinoma treatment is proposed.

16 cl, 56 dwg, 56 tbl

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RU 2 748 549 C2

Authors

Aftab, Dana, T.

Schwab, Gisela

Hessel, Colin

Scheffold, Christian

Lacy, Steven

Miles, Dale

Arroyo, Alan

Dean, Mark

Dates

2021-05-26—Published

2017-04-17—Filed