METHOD FOR TREATING THRICE-NEGATIVE BREAST CANCER Russian patent published in 2021 - IPC A61K31/47 A61P35/00 

Abstract RU 2757905 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to a method for treating thrice-negative breast cancer. The method for treating thrice-negative breast cancer in a human patient includes injection to a patient of a certain amount of cabosantinib (S)-malate, while the amount of cabosantinib (S)-malate is sufficient for activating one or more circulating biomarkers of the immune system, where cabosantinib (S)-malate is injected in a single dose of 20, 40 or 60 mg of a free base equivalent (FBE) of cabosantinib once a day in a tablet form containing 20, 40 or 60 mg of the free base equivalent (FBE) of cabosantinib. A method for treating thrice-negative HER2 breast cancer in a human patient and a method for treating thrice-negative breast cancer in a human patient with a certain sMET concentration are also disclosed.

EFFECT: group of inventions provides for activating biomarkers of the immune system.

12 cl, 7 dwg, 5 tbl, 1 ex

Similar patents RU2757905C2

Title Year Author Number
METHOD OF PREDICTING THE DEVELOPMENT OF METASTASES IN PATIENTS WITH UNRESECTABLE TRIPLE-NEGATIVE BREAST CANCER 2023
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Granov Dmitrii Anatolevich
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
  • Popova Alena Aleksandrovna
RU2802141C1
METHOD FOR DETERMINING THERAPEUTIC APPROACH IN PATIENTS WITH METASTATIC FORMS AND RECURRENT TRIPLE-NEGATIVE BREAST CANCER 2023
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Popova Alena Aleksandrovna
  • Semenov Konstantin Nikolaevich
  • Popova Elena Aleksandrovna
  • Protas Aleksandra Vladimirovna
  • Mikolaichuk Olga Vladislavovna
  • Sharoiko Vladimir Vladimirovich
  • Granov Dmitrii Anatolevich
RU2818730C1
METHOD FOR PREDICTING THE DURATION OF A RELAPSE-FREE PERIOD IN PATIENTS WITH RESECTABLE THRICE-NEGATIVE BREAST CANCER 2021
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Granov Dmitrii Anatolevich
  • Popova Alena Aleksandrovna
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
RU2780922C1
METHOD FOR PREDICTION OF LIFE EXPECTANCY IN PATIENTS WITH METASTATIC TUMORS 2023
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Popova Alena Aleksandrovna
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
  • Popova Elena Aleksandrovna
  • Protas Aleksandra Vladimirovna
  • Mikolaichuk Olga Vladislavovna
  • Granov Dmitrii Anatolevich
RU2821659C1
METHOD OF ASSESSING IMMEDIATE RESULTS OF TREATMENT OF PATIENTS WITH DISSEMINATED FORMS OF MALIGNANT TUMORS 2023
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Granov Dmitrii Anatolevich
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
RU2806483C1
COMBINATION THERAPY WITH SEMAFORIN 4D (SEMA4D) BLOCKING AND DC1 THERAPY 2020
  • Charnetski, Brajan
  • Kodumudi, Kritika
  • Evans, Elizabet
RU2801828C2
COMBINATION OF POXVIRUS ENCODING HUMAN PAPILLOMA VIRUS POLYPEPTIDES, AND IL-2 WITH ANTI-PD-L1 ANTIBODY 2020
  • Bendjama Kaidre
  • Brandely Talbot Maud
  • Tavernaro Annette
RU2824962C1
METHOD FOR ASSESSING THE SENSITIVITY OF A TUMOR TO IMMUNO-ONCOLOGICAL DRUGS 2021
  • Molchanov Oleg Evgenevich
  • Maistrenko Dmitrii Nikolaevich
  • Granov Dmitrii Anatolevich
  • Popova Alena Aleksandrovna
  • Semenov Konstantin Nikolaevich
  • Sharoiko Vladimir Vladimirovich
RU2771760C1
COMBINATION OF HDAC INHIBITOR AND ANTI-PD-1 ANTIBODY FOR TREATMENT OF CANCER 2016
  • Ordentlich, Peter
  • Goodenow, Robert
RU2796903C2
MOLECULES OF ANTIBODIES TO PD-1 AND THEIR USE 2016
  • Bilic, Sanela
  • Howard, Danny, Roland, Jr.
  • Cameron, John, Scott
  • Dranoff, Glenn
RU2788092C2

RU 2 757 905 C2

Authors

Tolaney, Sara, M.

Duda, Dan, G.

Dates

2021-10-22Published

2017-04-18Filed