SPECIFIC ANTIBODIES TO PD-L1 AND METHODS FOR THEIR APPLICATION Russian patent published in 2021 - IPC C07K16/28 C07K16/30 A61K39/395 A61P35/00 

Abstract RU 2749109 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to an antibody or its functional fragment that specifically binds to the human programmed cell death ligand 1 (PD-L1), as well as to the composition containing it. A method for inhibiting the proliferation of cancer cells in a subject is also disclosed, including the introduction of the above antibody or its functional fragment to a cancer-bearing subject.

EFFECT: invention makes it possible to effectively treat cancer in the subject.

28 cl, 6 dwg, 6 tbl, 9 ex

Similar patents RU2749109C2

Title Year Author Number
ANTI-INTERFERON BETA ANTIBODIES AND THEIR USE 2017
  • Gulla, Stefano, V.
  • Huard, Christine
  • Buhlmann, Janet, Elizabeth
  • Almagro, Juan, Carlos
  • Kodangattil, Sreekumar, R.
  • Greenberg, Steven, A.
  • Lavallie, Edward, Roland
  • Bennett, Eric, M.
  • Mosyak, Lidia
  • Hall, James, Perry
  • Coyle, Anthony, John
RU2750454C2
ANTI-PD-1 ANTIBODY 2015
  • Zha, Jiping
  • Sun, Ziyong
  • Qiu, Junzhuan
RU2722212C2
MONOSPECIFIC AND BISPECIFIC PROTEINS WITH IMMUNE CHECKPOINT REGULATION FOR CANCER TREATMENT 2018
  • Yu, Zhun-Zhe
  • Khsu, Ching-Khsuan
  • Khuan, Po-Lin
  • Kan, Khung-Tsaj
  • Chan, Tin-I
  • Khsiekh, Khsin-Ta
  • Kher, Dzheng-Khorng
RU2793167C2
NOVEL FUSION PROTEIN SPECIFIC FOR CD137 AND PD-L1 2019
  • Pavlidu, Marina
  • Pattarini, Lyuchiya
  • Sholer-Dairel, Aliks
  • Rote, Kristina
  • Olvill, Shejn
  • Bel Ajba, Rashida
  • Khinner, Marlon
  • Peper, Zhanet
RU2818349C2
BINDING MOLECULES, BINDING PD-L1 AND LAG-3 2017
  • Kempbell, Dzhejmi
  • Sendi, Nikol
  • Tyuna, Mikhriban
  • Vollerton Van Khork, Frantsiska
  • Everett, Keti Luiz
  • Gaspar, Migel
  • Kraman, Mettyu
  • Kmichik, Katarzhina
  • Farudi, Mustafa
  • Fosh, Natali
  • Khebeis, Barbara
RU2784388C2
ANTIBODIES TO PD-1 AND THEIR APPLICATION 2017
  • Mabry, George Robert, Iii
  • Sazinsky, Stephen
RU2761640C2
ANTI-PD-L1 AND IL-2 CYTOKINES 2017
  • Kempbell Dzhejmi
  • Sendi Nikol
  • Van Krinks Kassandra
  • Arkinstoll Stiven Dzhon
  • Germashevski Volker
  • Kerbi Ien
  • Kosmak Mikha
  • Gellager Tomas
  • Dintonio Sesiliya
  • Dzhillis Stiven Duglas
RU2769282C2
PD-L1 SPECIFIC ANTIBODIES 2017
  • Campbell Jamie
  • Sandy Nikole
  • Van Krinks Cassandra
  • Arkinstall Stephen John
  • Germaschewski Volker
  • Kirby Ian
  • Kosmac Miha
  • Gallagher Thomas
  • Deantonio Cecilia
  • Gillies Stephen Douglas
RU2756236C2
ANTIBODIES TO DOGS' PD-1 2014
  • Morsi Mokhamad
  • Chzhan Yuanchzhen
  • Bartels-Morozov Deniz
  • Erskin Dzhejson
  • Tarpi Ian
RU2732604C2
PD-L1 ANTIBODIES BINDING DOG PD-L1 2015
  • Morsey, Mohamad
  • Zhang, Yuanzheng
  • Bartels Morozov, Denise
  • Erskine, Jason
  • Tarpey, Ian
RU2722562C2

RU 2 749 109 C2

Authors

Belk, Dzhonatan

Sharki, Nejtan, Dzh.

Gorelik, Leonid

Dates

2021-06-04Published

2017-06-28Filed