FIELD: chemistry.
SUBSTANCE: invention relates to the compound of Formula (I)
,
in which R1 is С1-6alkyl; R2 is benzyl, with the specified benzyl not substituted or substituted by one, two or three substituents independently selected from the halogen and С1-6alkyl; R3 is -NR4R5, wherein R4 is С1-6alkyl or С1-6alkoxyС1-6alkyl; R5 is (С1-6alkyl)2NCOOC1-6alkyl, С1-6alkoxyС1-6alkyl, С1-6alkoxycarbonyl(С1-6alkyl)aminoС1-6alkyl, С1-6alkoxycarbonyl(phenyl)С1-6alkyl, С1-6alkoxycarbonylС1-6alkyl, С1-6alkoxycarbonyloxyС1-6alkyl, C1-6alkyl, С1-6alkylcarbonyl(С1-6alkyl)aminoС1-6alkyl or pyrrolidinylcarbamoyloxyС1-6alkyl or R4 and R5 together with the nitrogen atom to which they are attached, form a heterocyclyl; or its pharmacologically acceptable salt, enantiomer or diastereomer; to compositions containing these compounds, and to methods of using these compounds as agonists of Toll-like receptor 7 (TLR7).
EFFECT: proposed compounds can be used as Toll-like receptor 7 (TLR7) agonists.
25 cl, 7 dwg, 14 tbl, 57 ex
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