SOLUBILIZE WITH CURCUMIN, AND IF NECESSARY AT LEAST WITH ONE OTHER ACTIVE SUBSTANCE Russian patent published in 2021 - IPC A61K47/26 A61K31/05 A61K31/12 A61K31/122 A61K31/19 A61K31/385 A61K36/185 A61K36/324 A61K36/484 A61K38/48 A61K9/107 A61P25/16 A61P25/28 A61P29/00 A61P3/00 A61P3/04 A61P31/10 A61P35/00 A61P37/00 

Abstract RU 2752078 C1

FIELD: pharmaceutical industry.

SUBSTANCE: invention group relates to pharmaceutical industry, namely to an agent for the treatment and/or prevention of a disease selected from diseases including high cholesterol levels, high blood sugar levels, to reduce visceral fat, to lower cholesterol, to lower LDL cholesterol, and/or blood glucose and/or blood triglycerides, to reduce oxidative stress and/or to reduce the accumulation of fat in hepatocytes, to treat and/or prevent fatty liver disease. Following substances are presented: transparent, stable solubilizate containing: curcumin in an amount of 3 to 7 wt.%, boswellic acid in an amount of 4.7 to 10 wt.% and/or xanthohumol in an amount of 1 to 10 wt.%, polysorbate 80, or polysorbate 20 or a mixture of polysorbate 20 and polysorbate 80, where the polysorbate content is from 79 to 88 wt.%; a capsule for the treatment and/or prevention of the above diseases, filled with a solubilizate; liquid for the treatment and/or prevention of the above diseases, containing a solubilizate; a method of treating or preventing the above diseases; method of obtaining solubilizate (options).

EFFECT: above solubilizate has good transparency, is characterized by high bioavailability of curcumin, is effective for the treatment and/or prevention of a disease selected from diseases including high cholesterol, high blood sugar, to reduce visceral fat, to lower cholesterol, to lower LDL cholesterol, and/or blood glucose, and/or blood triglycerides, to reduce oxidative stress and/or to reduce the accumulation of fat in hepatocytes, to treat and/or prevent fatty liver disease.

20 cl, 4 dwg, 8 tbl, 9 ex

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RU 2 752 078 C1

Authors

Behnam, Dariush

Dates

2021-07-22Published

2018-07-11Filed