ANTI-LAG-3 ANTIBODIES AND THEIR COMPOSITIONS Russian patent published in 2021 - IPC C07K16/28 A61K39/395 A61P35/00 A61P37/00 A61P37/04 

Abstract RU 2755503 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry, in particular to an anti-LAG-3 antibody or its antigen-binding part, which specifically binds to LAG-3, a method for its production, as well as a composition containing it. A selected nucleic acid molecule encoding chains of the above-mentioned antibody, as well as a cell containing the above-mentioned nucleic acid are also disclosed. The invention also relates to a method for strengthening immunity in a patient providing for the use of the above-mentioned antibody or its part.

EFFECT: invention provides for the effective treatment of a patient with a LAG-3-related disorder.

25 cl, 9 dwg, 10 tbl, 14 ex

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RU 2 755 503 C2

Authors

Grandal, Michael Monrad

Bhatia, Vikram Kjoller

Gjetting, Torben

Frohlich, Camilla

Galler, Gunther Roland

Kragh, Michael

Horak, Ivan David

Bouquin, Thomas

Pedersen, Mikkel Wandahl

Dates

2021-09-16Published

2017-10-13Filed