HIGH-AFFINITY ANTI-PD-1 AND ANTI-LAG-3 ANTIBODIES AND BISPECIFIC BINDING PROTEINS OBTAINED FROM THEM Russian patent published in 2022 - IPC C07K16/28 A61K39/395 A61P35/00 

Abstract RU 2782381 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to bispecific polyvalent binding protein capable of binding PD-1 and LAG-3, as well as to an anti-LAG-3 antibody or its antigen-binding part. A composition containing the above-mentioned protein or antibody, as well as a method for the manufacture of a drug are also disclosed.

EFFECT: invention is effective for the treatment of a disorder, in which activity mediated by PD-1 and/or mediated by LAG-3 is harmful.

31 cl, 13 dwg, 55 tbl, 16 ex

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RU 2 782 381 C2

Authors

Wu, Xuan

Gong, Shiyong

Wu, Chengbin

Dates

2022-10-26Published

2019-04-30Filed