ANTI-PCSK9 ANTIBODY AND ITS APPLICATION Russian patent published in 2021 - IPC C07K16/40 C12N15/13 A61K39/395 A61P3/06 

Abstract RU 2756012 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry, in particular to an antibody, which specifically binds to PCSK9. A pharmaceutical composition containing the specified antibody; a nucleic acid molecule encoding the specified antibody; a vector and a host cell containing the specified nucleic acid molecule; an immunoconjugate containing the specified antibody are also disclosed. The application of the specified antibody in production of a drug for the treatment of dyslipidemia or a drug for facilitating cellular capture of low-density lipoproteins (LDL) is disclosed.

EFFECT: invention has the capability of effective treatment of diseases related to PCSK9.

15 cl, 14 dwg, 3 tbl, 17 ex

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RU 2 756 012 C2

Authors

Wu Hai

Chen Bo

Feng Hui

Yao Sheng

Yao Jian

Liu Hongchuan

Zhang Libo

Zhang Jing

Meng Dan

Dates

2021-09-24Published

2016-11-24Filed