IL-5 BINDING MOLECULE, METHOD OF ITS PREPARATION AND ITS USE Russian patent published in 2024 - IPC C07K16/24 C12P21/02 A61K39/395 A61P37/00 G01N33/53 A61K51/10 

Abstract RU 2811518 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to recombinant IL-5-binding molecules, and can be used in medicine in the production of drugs targeting IL-5 for the treatment of leukemia. The following is proposed: an IL-5-binding molecule capable of specifically binding to interleukin-5 (IL-5) and containing a single immunoglobulin variable domain with a defined set of complementarity determining regions CDR1, CDR2 and CDR3.

EFFECT: invention makes it possible to obtain a molecule capable of specifically binding to IL-5 and effectively blocking cell proliferation induced by IL-5.

14 cl, 8 dwg, 10 tbl, 5 ex

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RU 2 811 518 C1

Authors

Su, Zhipeng

Meng, Jinguo

Zhang, Yun

Wang, Lefei

Yao, Yao

Dates

2024-01-12Published

2021-02-24Filed