METHOD FOR TREATING MULTIPLE SCLEROSIS Russian patent published in 2021 - IPC A61K39/395 A61P25/00 

FIELD: medicine.

SUBSTANCE: group of inventions relates to a method for improving functional capacity in a patient having multiple sclerosis, comprising administering to the patient an effective amount of anti-CD20 antibody, wherein the patient has improved functional capacity after administration and where the functional capacity improvement is maintained for at least 12 weeks; where anti-CD20 antibody contains: a) a heavy chain variable region comprising CDR1 having the amino acid sequence SEQ ID NO: 10, CDR2, having amino acid sequence SEQ ID NO: 11, and CDR3 having the amino acid sequence SEQ ID NO: 12, and b) a light chain variable region containing CDR1 having the amino acid sequence SEQ ID NO: 4, CDR2 having the amino acid sequence SEQ ID NO: 5, and CDR3, having amino acid sequence SEQ ID NO: 6. Group of inventions also relates to a method of reducing the average annual recurrence rate in a human patient having multiple sclerosis; kit for treating multiple sclerosis in a patient in accordance with said method.

EFFECT: group of inventions provides improved functional capacity in the patient suffering multiple sclerosis.

58 cl, 34 dwg, 14 tbl, 2 ex