FIELD: chemistry.
SUBSTANCE: invention relates to a method for producing 3-aryl-7-diphenylspiro[furo [3',4':2,3]pyrrolo[1,2-а]quinoxaline-5,3'-indoline]-1,2,2', 6(7H)-tetraones of the general formula
,
where R1=NO2 (Ia); R1=Cl (Ib); R1=CH3 (Ic), which consists in the fact that 3-aroyl-5-phenylpyrrolo[1,2-а]quinoxalin-1,2,4(5H)-triones are reacted with 3-diazoindolin-2-one in acetonitrile medium, followed by isolation of the target products.
EFFECT: method has been developed for preparing new compounds that can be used in medicine as antimicrobial drugs.
1 cl, 4 ex, 1 tbl
| Title |
Year |
Author |
Number |
| 3-ARYL-6H-SPIRO[BENZO[b]FURO[3',4':2,3]PYRROLO[1,2-d][1,4]OXAZINE 5,3'-INDOLINE]-1,2,2',6-TETRAONES WITH ANTI-INFLAMMATORY ACTIVITY, AND THE METHOD FOR THEIR PREPARATION |
2021 |
- Mashevskaya Irina Vladimirovna
- Apushkin Danila Yurevich
- Andreev Aleksandr Igorevich
- Topanov Pavel Andreevich
|
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| APPLICATION OF 3-ARYLSPIRO[FURO[3',4':2,3]PYRROLO[1,2-a]QUINOXALINE-5,3'-INDOLINE]-1,2,2',6(7H)-TETRAONES AS AGENTS WITH ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES |
2023 |
- Mashevskaia Irina Vladimirovna
- Topanov Pavel Andreevich
- Balandina Svetlana Iurevna
|
RU2806192C1 |
| USE OF 3-ARYL-6H-SPIRO[BENZO[b]FURO[3',4':2,3]PYRROLO[1,2-d][1,4]OXAZINE-5,3'-INDOLINE]-1, 2,2',6-TETRAONES AS AGENTS WITH ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES |
2023 |
- Mashevskaia Irina Vladimirovna
- Topanov Pavel Andreevich
- Balandina Svetlana Iurevna
|
RU2806194C1 |
| 3-(4-CHLOROPHENYL)SPIRO[FURO[3',4':2,3]PYRROLO[1,2-A]QUINOXALINE-5,3'-INDOLINE]-1,2,2',6(7H)-TETRAONE HAVING ANTI-INFLAMMATORY ACTIVITY AND A METHOD FOR PRODUCTION THEREOF |
2021 |
- Mashevskaya Irina Vladimirovna
- Chashchina Svetlana Viktorovna
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|
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2023 |
- Mashevskaia Irina Vladimirovna
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|
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2023 |
- Mashevskaia Irina Vladimirovna
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- Balandina Svetlana Iurevna
- Dmitriev Maksim Viktorovich
|
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2021 |
- Mashevskaya Irina Vladimirovna
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- Lukmanova Dzhamilya Nailevna
|
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| 2-AMINO-6-HYDROXY-7-(3-OXO DIHYDROQUINOXALINE-2-yl)-7a-PHENYL-PYRROLO[2,1-b][1,3,4]THIADIAZOLE-5(7aH)-ONS WITH ANTI-INFLAMMATORY ACTIVITY, AND THE METHOD FOR THEIR PREPARATION |
2021 |
- Mashevskaya Irina Vladimirovna
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- Apushkin Danila Yurevich
- Utushkina Taisiya Andreevna
- Yakushina Karolina Evgenevna
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|
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| 2-ARYL-2,4-DIHYDROXY-2,5-DIHYDRO-3-HETERYL-5-OXO-1H-PYRROL-1-YL-4-METHYL BENZENESULPHANOLAMIDES WITH ANALGESIC ACTIVITY |
2015 |
- Suchkova Nadezhda Vladimirovna
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
- Mashevskaya Irina Vladimirovna
|
RU2626650C2 |
| 4 - ((2-ARYL-2,4-DIHYDROXY-5-OXO-3-(3-OXO-3,4-DIHYDROQUINOXALIN-2-YL)-2,5-DIHYDRO-1N-PYRROL-1-YL)AMINO)BENZOIC ACIDS HAVING ANALGESIC ACTIVITY |
2019 |
- Mashevskaya Irina Vladimirovna
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|
RU2731215C1 |
