USE OF 3-ARYL-6H-SPIRO[BENZO[b]FURO[3',4':2,3]PYRROLO[1,2-d][1,4]OXAZINE-5,3'-INDOLINE]-1, 2,2',6-TETRAONES AS AGENTS WITH ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES Russian patent published in 2023 - IPC A61K31/5383 A61P31/04 A61P31/10 C07D498/22 

Abstract RU 2806194 C1

FIELD: organic chemistry.

SUBSTANCE: invention is related to the use of individual compounds of the class 3-aryl-6H-spiro[benzo[b]furo[3',4':2,3]pyrrolo[1,2-d][1,4]oxazine-5,3'-indoline]-1,2,2',6-tetraones 3a-g as agents with antibacterial and antifungal activities, where R1=H, R2=H, R3=H (3a), R1=H, R2=Br, R3=H (3b), R1=H, R2=H, R3=Br (3c), R1=H, R2=NO2, R3=H (3d), R1=Cl, R2=H, R3=H (3e), R1=H, R2=H, R3=OCH3 (3f), R1=H, R2=OCH3, R3=H (3g).

EFFECT: compounds of formula 3a-3g exhibit antibacterial and antifungal activity.

1 cl, 1 tbl, 8 ex

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RU 2 806 194 C1

Authors

Mashevskaia Irina Vladimirovna

Topanov Pavel Andreevich

Balandina Svetlana Iurevna

Dates

2023-10-27Published

2023-03-28Filed