FIELD: immunology.
SUBSTANCE: isolated antibody is proposed that specifically recognizes galactan-III epitope of lipopolysaccharide (LPS) O-antigen structure from Klebsiella pneumoniae, and does not cross-react with galactan-I epitope. Besides, a pharmaceutical preparation, the use of the antibody, diagnostic preparations, a method for diagnosing infection or Klebsiella pneumoniae colonization are proposed. Isolated nucleic acid, an expressing cassette or plasmid, a host cell, and a method for producing antibody are also proposed.
EFFECT: present invention can be used in the therapy or diagnostics of Klebsiella pneumoniae infection.
17 cl, 12 dwg, 6 tbl, 8 ex
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