FIELD: biochemistry.
SUBSTANCE: invention relates to a bispecific diabody molecule specifically binding to an immune effector cell CD3 epitope and an epitope of an antigen expressed by an HIV-infected cell, as well as to a bispecific diabody molecule specifically binding to an immune cell effector cell epitope CD16 and an epitope of an antigen expressed by an HIV-infected cell. Also disclosed is a pharmaceutical composition containing said diabody. Invention also relates to use of said bispecific diabody molecule for treating latent, persistent and inactive HIV infection.
EFFECT: invention enables effective treatment of HIV infection.
24 cl, 7 dwg, 1 tbl, 8 ex
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Authors
Dates
2020-05-21—Published
2014-03-13—Filed