COMPOSITION FOR INJECTION BASED ON PHOSPHOTIDYLCHOLINE, METHIONINE, VITAMIN E AND SODIUM SELENITE - "HEPARS", WHICH HAS HEPATOPROTECTIVE PROPERTIES, AND A METHOD FOR ITS PREPARATION Russian patent published in 2021 - IPC A61K9/10 A61K31/14 A61K31/355 A61K31/198 A61K33/04 A61P1/16 

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to the field of pharmaceuticals. The hepatoprotective injection pharmaceutical composition contains phosphatidylcholine, vitamin E, methionine and sodium selenite, as well as the surfactant TWIN-80, the organic pharmacopoeial solvent 2-pyrrolidone, benzyl alcohol and water, from which the micellar form is formed, using the following ratio of substances: phosphatidylcholine 0.24 g, vitamin E 0.02 g, methionine 0.04 g, sodium selenite 0.0011 g, benzyl alcohol 0.1 ml, 2-pyrrolidone 3.5 ml, TWIN-80 0.8 ml, water 5.3 ml.

EFFECT: composition is characterized by low toxicity, the ability to target transport, controlled release in the target area, as well as chemical and physical stability during storage.

1 cl, 38 tbl