EXENATIDE ANALOGUE CONJUGATES WITH DELAYED RELEASE Russian patent published in 2022 - IPC A61K38/00 C07K14/605 

Abstract RU 2764547 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, specifically to a new conjugate of a stabilized agonist of a glucagon-like peptide-1 (GLP-1) receptor; it can be used in medicine. The invention allows for producing the conjugate with improved pharmacological properties: delayed release balances the agonist stability with the speed of release in the organism environment, providing its longer action in comparison with known analogues.

EFFECT: invention can be used in medicinal practice, when treating patients suffering from diabetes or other similar metabolic disorders, using schemes including the administration of a dose once a month or less.

16 cl, 16 dwg, 2 tbl, 8 ex

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RU 2 764 547 C2

Authors

Schneider, Eric L.

Hearn, Brian

Henise, Jeffrey C.

Ashley, Gary W.

Santi, Daniel, V.

Dates

2022-01-18Published

2017-03-16Filed