FUSED DRUG CONSTRUCTS AND CONJUGATES Russian patent published in 2011 - IPC C07K16/46 

Abstract RU 2428431 C2

FIELD: medicine.

SUBSTANCE: what is described are drug conjugates which contain an incretin therapeutic or diagnostic agent who is fused or conjugated with an antigen-binding antibody fragment which binds serum albumin.

EFFECT: conjugates have prolonged in vivo half-life in comparison with an unconjugated or unfused therapeutic or diagnostic agent.

27 cl, 19 dwg, 8 tbl, 18 ex

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Authors

Kholms Stiv

Khoult Ljusi Dzh.

Dzhespers Lorent S.

Tomlinson Ajan M.

Dates

2011-09-10Published

2005-11-30Filed