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(19)

(11)

2 769 701

(13)

(51)

IPC

A61K38/10(2006-01-01)

A61K47/02(2006-01-01)

A61P7/00(2006-01-01)

A61M5/00(2006-01-01)

(21) (22)

Application

2020131790, 2016-12-07

(24)

Start date

2016-12-07

(22)

Actual filing date

2016-12-07

(45)

Published

2022-04-05

(72)

Inventor

Demarco, Steven JamesHoarty, Michelle DeniseParker, Grace VictoriaRicardo, AlonsoTobe, SylviaTreco, Douglas A.

(73)

Holder

Ra Pharmaceuticals, Inc.

COMPLEMENT ACTIVITY MODULATORS Russian patent published in 2022 - IPC A61K38/10 A61K47/02 A61P7/00 A61M5/00

Abstract RU 2769701 C2

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions relates to polypeptide complement activity modulators. Disclosed is an aqueous pharmaceutical composition for inhibiting the activation of the C5 complement component, including a C5 inhibitor polypeptide with the basic sequence SEQ ID NO: 1, salt, and a buffer agent. Also disclosed is an application of said composition for treating a complement-related disorder in a patient and an auto-injection apparatus including said composition.

EFFECT: claimed group of inventions makes provides a possibility of selectively blocking complement-mediated cell destruction.

15 cl, 20 dwg, 18 tbl, 15 ex

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RU 2 769 701 C2

Authors

Demarco, Steven James

Hoarty, Michelle Denise

Parker, Grace Victoria

Ricardo, Alonso

Tobe, Sylvia

Treco, Douglas A.

Dates

2022-04-05—Published

2016-12-07—Filed